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Mesothelioma and Non Asbestos Exposure Most commonly, mesothelioma develops on the lung linings as well as the abdomen. This rare cancer may develop in the linings around the heart or testes (pericardium). Asbestos exposure is a major risk factor for mesothelioma. Certain mesothelioma patients do not have a prior history of exposure to asbestos. Exposure to Asbestos Asbestos is a mineral that is natural that was once used in construction and industrial products worldwide. The workers in asbestos industries handled the mineral on a regular basis, putting them at risk of exposure. Asbestos particles can be trapped in the lungs, which can lead to progressive lung diseases. This is known as asbestosis. Over time, these fibers trapped in the lungs can also cause mesothelioma. Asbestos can also be inhaled or consumed, and the risk of developing mesothelioma and other asbestos-related illnesses increases with the length and quantity of exposure. The majority of mesothelioma cases result from occupational exposure. Asbestos was employed in various trades, including construction, insulation, electrical work, automobile maintenance and pipefitting. As these trades are mostly dominated by males 75-80% of mesothelioma patients are males. However, the phasing out of asbestos in the United States and other first-world countries has decreased on-the-job exposure. This has led to a shift in the number of cases, with asbestos exposure in non-occupational settings becoming more frequent. Non-occupational Mesothelioma occurs when asbestos is released in the workplace or at the home or in schools. The secondhand exposure can also trigger it, for instance, when a family member touches the clothes worn by an asbestos worker. This kind of exposure can cause symptoms like chest pain or a shortness of breath that are often mistaken for heart problems or lung diseases. Certain studies have linked non-occupational exposure to mesothelioma, but the results are not consistent. The studies were conducted with only a few participants, and the variability between studies was high. It is necessary to conduct additional studies to confirm the link between asbestos exposure from non-occupational sources and mesothelioma. Those with non-occupational exposure should discuss their asbestos medical history with their doctor. If they are concerned, they should ask for mesothelioma screening and a referral to an expert. Mesothelioma specialists can provide patients with the most effective treatment and care options to improve their prognosis. They will review medical records, and perform imaging tests to determine the disease. They will also provide guidance on how to file a mesothelioma lawsuit to get compensation from an asbestos trust fund. Secondhand Exposure While exposure to asbestos is the primary cause of mesothelioma not the only factor that can cause you to develop this disease. In fact, there's some evidence that suggests that people may develop mesothelioma, even if they have never directly handled asbestos or worked in an industry that involved asbestos-related activities. This is known as secondary or non-occupational exposure to asbestos. Asbestos fibres are very small and can adhere to clothing, hair and skin. Workers can carry dangerous fibers in their work clothing at home and then transfer them to family members. These asbestos fibers can cause mesothelioma if inhaled or ingestion. This type of mesothelioma is more prevalent in women, and it usually occurs in the lung. However, it can be found in the abdomen or chest wall. The most commonly reported symptoms is breathlessness (dyspnea), and it is often associated with other symptoms such as fluid in the lungs, or a swelling in the scrotum. The mesothelioma that develops in the lungs is referred to as pleural mesothelioma. Mesothelioma that is affecting the chest wall, stomach, or is called peritoneal mesothelioma. A person with this type of mesothelioma might experience a variety of symptoms such as abdominal pain, breathing difficulties and constipation. Several studies have reported that individuals with no previous history of exposure to asbestos may develop mesothelioma due to exposure to harmful fibers. In most cases, they have been living with someone who was exposed to the dangerous substance. They could have handled the garments of the worker, or they might have had other exposure to asbestos. Veterans are at a high risk of mesothelioma because asbestos was widely used in military bases, vehicles and ships. The Navy is especially at risk due to asbestos being used to insulate the hull the ship as well as to protect gun turrets. In addition, sailors frequently brought home asbestos from their jobs on ships that were contaminated by asbestos. Environmental Exposure Mesothelioma has been linked to a variety of substances. However, the condition is usually linked to exposure to asbestos. Asbestos, a naturally occurring mineral was used in the manufacturing process for a long time. It is a heat-resistant material and durable which makes it suitable for insulation, brakes and shingles, flooring, and other products. When asbestos is broken down it releases dust which can be inhaled or swallowed. The asbestos fibers can stay in the stomach or lungs for years, and trigger mesothelioma symptoms. The most common mesothelioma symptoms are chest pain, abdominal discomfort and difficulty breathing. Asbestos sufferers may experience these symptoms for 20 to 60 years or more after their first exposure. These symptoms could be mistaken for other diseases, therefore it is important to see an expert if you experience these symptoms. It is also critical to tell your doctor about your past history of asbestos. This can help avoid a false diagnosis and ensure that you receive the proper treatment. The most commonly affected mesothelioma victims from asbestos exposure are those who have worked directly with asbestos, but it is also possible for loved relatives to be affected. This is known as secondary exposure. Family members could inhale or swallow asbestos fibers on the clothing of a worker, shoes, or other tools. They may also be exposed to asbestos by someone who brings home these particles on their clothing or hair. This is the reason mesothelioma sufferers and their families must be sure to wash their clothing properly after working around asbestos. There is a substantial collection of studies that show an association between exposure to nonasbestos and mesothelioma. However, there are no definitive conclusions yet about the role of other agents. For instance, there is some evidence that the zeolites erionite and chrysotile may cause mesothelioma. Erionite is found in the soil and rocks from certain regions in Turkey where the rate of mesothelioma pleural is high. The study of the relationship between nonasbestos and mesothelioma is ongoing. Funnel plots have shown the potential for publication bias, and between-study heterogeneity is high. It is evident that asbestos exposure is the main mesothelioma-related risk factor. Genetics Mesothelioma is an uncommon disease caused by malignant mesothelial cell that expand beyond control and invade surrounding tissues. It can be spread throughout the body by traversing the bloodstream or lymphatic system and affecting other organs. Asbestos is the primary reason, but it's not the only factor. Other genetic and environmental factors can cause the condition. In some cases mesothelioma is seen in people who were not exposed to asbestos. They are known as non-occupational mesothelioma patients. They were usually exposed indirectly by the handling of contaminated clothing or household items by someone who was exposed asbestos in their home. For instance, it's possible for someone to be diagnosed with pleural mesothelioma based on the exposure to asbestos fibers in clothing belonging to a loved ones. Research has shown that this form of mesothelioma has an extended latency time and is more likely to be affecting women than men. Scientists are examining the possibility that mesothelioma-related genetic predispositions could play a role in its development. Recent studies have demonstrated that the mutation of BAP1 gene increases the risk of mesothelioma in asbestos-exposed patients. Anchorage asbestos lawsuit is a significant finding, as it could lead to improved screening procedures for those at risk of developing mesothelioma. Researchers have discovered that a range of genes are linked to mesothelioma. Some of these genes are involved in suppressing tumor growth and are often mutated or altered in mesothelioma patients. These genes include the massive homolog of tumor suppressor 2 (LATS2) and NF2. People with a family history of mesothelioma are at a higher chance of contracting the cancer. This is because some genes, like BAP1 BAP1, can be inherited from a parent. Asbestos was a common ingredient in the military for a number of years, and veterans have the highest rates of mesothelioma compared to other occupational groups. People who were in the Navy and on ships were particularly at greatest risk because of the extensive exposure to asbestos in insulation, fireproofing materials and shipbuilding.